Severe Babesia microti Infection in an Immunocompetent Host in Pennsylvania

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Severe Babesia microti Infection in an Immunocompetent Host in Pennsylvania

Babesiosis, due to infection by a tick-borne protozoan (predominantly Babesia microti in North America), is an emerging health risk that is expanding into new areas and may be unfamiliar to clinicians in locations not previously considered endemic. Manifestations of infection can range from asymptomatic to life threatening, with severe disease more likely in those who have had a splenectomy, ar...

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Babesia microti Infection, Eastern Pennsylvania, USA

Infection with Babesia microti has not been well-described in eastern Pennsylvania, USA, despite the vector of this organism being prevalent. We report 3 cases of babesiosis in eastern Pennsylvania in persons without recent travel outside the region or history of blood transfusions, suggesting emergence of this infection.

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Babesia microti: an unusual travel-related disease

BACKGROUND Human babesiosis is a rare tick-borne infectious disease. The clinical presentation ranges from an asymptomatic form to a life threatening infection with severe hemolysis. Human babesiosis due to Babesia microti is the most common and is endemic in North America. CASE PRESENTATION We report a European patient with severe pancytopenia and reactive hemophagocytosis related to a Babes...

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Reservoir Competence of Wildlife Host Species for Babesia microti

Human babesiosis is an increasing health concern in the northeastern United States, where the causal agent, Babesia microti, is spread through the bite of infected Ixodes scapularis ticks. We sampled 10 mammal and 4 bird species within a vertebrate host community in southeastern New York to quantify reservoir competence (mean percentage of ticks infected by an individual host) using real-time P...

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Babesia microti Infection Changes Host Spleen Architecture and Is Cleared by a Th1 Immune Response

Babesia microti is a malaria-like parasite, which infects ∼2000 people annually, such that babesiosis is now a notifiable disease in the United States. Immunocompetent individuals often remain asymptomatic and are tested only after they feel ill. Susceptible C3H/HeJ mice show several human-like disease manifestations and are ideal to study pathogenesis of Babesia species. In this study, we exam...

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ژورنال

عنوان ژورنال: Journal of Investigative Medicine High Impact Case Reports

سال: 2016

ISSN: 2324-7096,2324-7096

DOI: 10.1177/2324709616663774